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KMID : 0869619960130020114
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Journal of Korean Society of Hospital Pharmacists
1996 Volume.13 No. 2 p.114 ~ p.118
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Drug Use Evaluation on Metronidazole for Hospitalized Adult Patients
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박은자/Park, Eun Ja
김상현/박경호/이병구/조남춘/최강원/Kim, Sang Hyun/Park, Kyoung Ho/Lee, Byung Koo/Cho, Nam Choon/Choe, Kang Won
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Abstract
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A retrospective drug use evaluation (DUE) of intravenous metronidazole was conducted for hospitalized adult patients. Criteria for DUE on metronidazole modified from those suggested by Am. J. Hosp. Pharm. The charts of 73 patients were reviewed from July 1. 1995 to July 31. 1995 in Seoul National University Hospital. The results were analyzed in two groups, department of Internal Medicine and Surgery. The justification of use was 54.8% in Medicine and 76.2% in Surgery. Several criteria including body temperature monitering, WBC monitoring, CBC, LFT before initial dose were well documented. Criteria for duration of therapy were well documented. Metronidazole was injected not to exceed for 4 weeks every cases. In outcome analysis, blood culture after discontinuing drug was rarely documented, with accepted level of 48.4% in Medicine and 35.7% in Surgery. It was considered that communication to medical staffs about these findings is important factor to induce the optimal usage of metronidazole.
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